Rotem Karni Selected Research

RNA Splicing Factors

1/2019	Specific inhibition of splicing factor activity by decoy RNA oligonucleotides.
1/2017	Long Noncoding RNA MALAT1 Promotes Hepatocellular Carcinoma Development by SRSF1 Upregulation and mTOR Activation.
3/2016	Heterogeneous nuclear ribonucleoproteins A1 and A2 modulate expression of Tid1 isoforms and EGFR signaling in non-small cell lung cancer.
1/2015	The role of splicing factors in deregulation of alternative splicing during oncogenesis and tumor progression.
4/2014	Splicing factor hnRNP A2 activates the Ras-MAPK-ERK pathway by controlling A-Raf splicing in hepatocellular carcinoma development.
11/2013	RRM1 domain of the splicing oncoprotein SRSF1 is required for MEK1-MAPK-ERK activation and cellular transformation.
3/2013	The splicing factor SRSF6 is amplified and is an oncoprotein in lung and colon cancers.
1/2012	The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation.
7/2011	Splicing factor hnRNP A2/B1 regulates tumor suppressor gene splicing and is an oncogenic driver in glioblastoma.
1/2011	Alternative splicing of SLC39A14 in colorectal cancer is regulated by the Wnt pathway.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Rotem Karni Research Topics

Disease

29	Neoplasms (Cancer) 01/2021 - 02/2003
4	Hepatocellular Carcinoma (Hepatoma) 01/2019 - 04/2014
4	Carcinogenesis 01/2017 - 01/2011
4	Breast Neoplasms (Breast Cancer) 06/2016 - 01/2012
3	Glioblastoma (Glioblastoma Multiforme) 11/2018 - 07/2011
2	Adenocarcinoma of Lung 01/2019 - 06/2016
2	Neoplasm Metastasis (Metastasis) 01/2019 - 06/2016
2	Hypoxia (Hypoxemia) 01/2017 - 11/2002
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2021
1	Pre-Eclampsia (Preeclampsia) 10/2020
1	Lung Neoplasms (Lung Cancer) 03/2016
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 03/2016
1	Insulin Resistance 01/2016
1	Liver Neoplasms (Liver Cancer) 04/2014
1	Inflammation (Inflammations) 04/2014
1	Basal Cell Carcinoma (Rodent Ulcer) 08/2013
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 08/2013
1	Colonic Neoplasms (Colon Cancer) 03/2013
1	Malaria 10/2012
1	Colorectal Neoplasms (Colorectal Cancer) 01/2011

Drug/Important Bio-Agent (IBA)

13	RNA Splicing FactorsIBA 01/2019 - 03/2007
12	Protein Isoforms (Isoforms)IBA 01/2021 - 03/2007
4	Oncogene Proteins (Oncogene Protein)IBA 03/2013 - 03/2007
3	Long Noncoding RNAIBA 01/2019 - 06/2016
3	Proteins (Proteins, Gene)FDA Link 01/2017 - 01/2011
2	Biological ProductsIBA 01/2019 - 10/2012
2	OligonucleotidesIBA 11/2018 - 12/2017
2	RNA (Ribonucleic Acid)IBA 01/2017 - 05/2015
2	RNA Precursors (Precursor, mRNA)IBA 06/2016 - 03/2016
2	Heterogeneous Nuclear Ribonucleoprotein A1IBA 03/2016 - 04/2014
2	hnRNP A2IBA 04/2014 - 07/2011
2	Arginine (L-Arginine)FDA Link 11/2013 - 03/2010
2	Serine (L-Serine)FDA Link 11/2013 - 03/2010
2	Eukaryotic Initiation Factor-4EIBA 01/2012 - 03/2007
2	Phosphotransferases (Kinase)IBA 01/2011 - 03/2007
1	epidermal growth factor receptor VIIIIBA 02/2020
1	ErbB Receptors (EGF Receptor)IBA 02/2020
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2019
1	Glucose (Dextrose)FDA LinkGeneric 01/2019
1	Transcription Factor 7-Like 2 ProteinIBA 01/2019
1	Antisense RNA (Anti-Sense RNA)IBA 11/2018
1	Peptides (Polypeptides)IBA 12/2017
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2017
1	LipidsIBA 01/2017
1	Nucleic AcidsIBA 01/2017
1	Heterogeneous-Nuclear Ribonucleoproteins (Informatin)IBA 03/2016
1	Insulin ReceptorIBA 01/2016
1	Insulin (Novolin)FDA Link 01/2016
1	Folic Acid (Vitamin M)FDA LinkGeneric 09/2015
1	insulin-like growth factor binding protein-related protein 1IBA 08/2013
1	Messenger RNA (mRNA)IBA 08/2013
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2013
1	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 01/2013
1	Small Interfering RNA (siRNA)IBA 01/2011
1	CateninsIBA 01/2011
1	CationsIBA 01/2011
1	MTOR InhibitorsIBA 10/2008
1	Proto-Oncogene Proteins pp60(c-src) (pp60 c-src)IBA 06/2005
1	src-Family KinasesIBA 02/2003
1	Transcription Factors (Transcription Factor)IBA 11/2002

Therapy/Procedure

6	Therapeutics 01/2021 - 03/2007
2	Drug Therapy (Chemotherapy) 01/2019 - 11/2018
1	Immunotherapy 01/2021
1	Mohs Surgery (Mohs' Micrographic Surgery) 08/2013
1	Transplantation 01/2012